Top Bioanalytical Services Companies
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Pharma Tech Outlook: Pharma Tech Magazine

Xyzagen, Inc.: Powering The Evolving Drug Discovery Landscape

Top 10 Bioanalytical Services Companies - 2020

While the entire drug development process has evolved tremendously over time, bioanalytics—the foundation of drug development— remains labor-intensive and technically challenging. Despite recent advances involving the combination of traditional and new technologies, there is an urgent need for novel approaches in bioanalytics to increase throughput and improve drug development quality. To that end, the pharma community has employed new types of technologies and tools—traditionally used in a clinical laboratory—setting, such as the use of MesoScale devices and flow cytometry. As a well-established tool for biomarker analysis, flow cytometry has shifted from its origins in the clinical diagnostic laboratories to the regulated bioanalytical laboratory. Beyond whole-cell analysis for drugs such as CAR-T cells medicines, flow cytometry has applications in assisted biomarker and ADA testing.

That being said, the pressure to accelerate critical tasks, such as data transformation, analysis, and follow-on decision-making, continually expands in all phases of drug development. For example, within early clinical-stage bioanalysis, data review for large reports ideally requires 14 days to account for the multi-layered input involving stakeholders spanning bioanalytical scientists, management, quality control, and quality assurance. AI is well-positioned to handle not only the high volumes of bioanalytical data but also manage the complexity of the rules that must be applied to link and contextualize disparate data in key functions of assay development and sample analysis.

Today, pharma manufacturers are seeking analytical testing service providers to look for quality in terms of technical performance—the quality of the data and work performed—as well as with respect to regulatory compliance. Bioanalytical service providers have a deep understanding of the drug development process and extensive knowledge of regulatory requirements, combined with the ability and willingness to provide customized support. Hence, they are often viewed as real added value.

At this juncture, there are a wide variety of bioanalytical service providers in the pharma industry offering innovative services that further the drug development cycle. To help organizations navigate through the best-of-breed companies, Pharma Tech Outlook has compiled a list of leading bioanalytical services firms that are at the top of their game. The enlisted organizations are transforming the drug development process at the convergence of several disruptive technologies. Besides, the magazine also comprises insights from thought leaders in the sector on the industry trends, best practices, recent innovations, and their advice for aspiring CIOs.

We present to you Pharma Tech Outlook’s “Top 10 Bioanalytical Services Companies – 2020.”

Top Bioanalytical Services Companies

By combining specialised expertise, technological innovation and a 20-year track record, Agilex Biolabs supports hundreds of preclinical and clinical trials around the world. The company delivers quality every time, for every project. The clients choose Agilex because it the recognised leaders in bioanalytical excellence with 20 years of experience. The company is strategically co-located in the Tech Hub, in Adelaide, South Australia, which fosters innovation, collaboration, knowledge transfer and support for technology companies. Its world-class FDA inspected bioanalytical facilities have OECD GLP recognition with NATA (Australian Government OECD GLP compliance monitoring authority) and ISO 17025 Accreditation

www.agilexbiolabs.com

BioPharma Services was founded by physicians dedicated to advancing medical science to improve the life and spirit of their patients. With this dedication and vision in mind, these physicians brought life to BioPharma, creating a core team of leaders that together would inspire growth and innovation through teamwork and collaboration. Today, BioPharma is a contract research organization and CRO company that operates with a flourishing team of 250+ employees across two research sites in Canada and the USA

www.biopharmaservices.com

ChemoGenicsBioPharma is a drug discovery research and service-based organization that offers one-stop, high-quality, and economically feasible solutions for preclinical drug discovery.The company offers exceptional services in medicinal chemistry, process optimization, scale-up, animal (rodent) dosing studies, DMPK, and bioanalytical studies (tissue and plasma matrices). When clients approach ChemoGenicsBioPharmato design and develop new molecules, they also opt for the company’s other extensive capabilities—including molecular modeling, in-house bioanalytical services, and compound scale-up. The company also conducts collaborative research with clients, helping them transform their ideas into viable drug candidates

chemogenicsbiopharma.com

Ology Bioservices, Inc. is a biologics-focused, full-service CDMO, offering bioanalytical development and testing services. The Ology Bio Bioanalytical Services team has significant experience in the Biopharma industry in GLP- and GMP-regulated roles, developing quality products that meet the clients’ needs in a timely and compliant manner. The team has extensive expertise in designing, developing, troubleshooting, and validating ligand-binding assays for pharmacokinetics, pharmacodynamics, and immunogenicity assessment in biotherapeutic programs

www.ologybio.com

S-BIO specializes in providing high-performance labware: Quality 3D Cell Culture products for regenerative medicine, low bind products essential for proteins, peptides and cell recovery and high-throughput kits and services for N-glycan and O-glycan analysis. S-BIO is a part of Healthcare Business Division of Sumitomo Bakelite Co., Ltd. (A pioneer in plastics with products used for a wide range of applications such as IT components and material, high-performance plastics and quality-of-life product). S-BIO’s products are distributed in North America by Vaupell, a subsidiary of Sumitomo Bakelite Co., Ltd. Vaupell is located at Hudson, New Hampshire. S-BIO’s life science products include high-performance 3D cell culture labware and a wide range of glycan analysis solutions

s-bio.com

Xyzagen is a focused bioanalytical, PK and integrated early in vivo rodent Pharmacology contract research organization & consulting firm. Our contract research & consultancy focus is on early to mid-stage biotech start-ups. As a consulting firm, Xyzagen is focused on not just offering a service but rather being a team member who is invested in the client's success. Besides, as consultants and drug developers, Xyzagen can tailor its bioanalytical services to be "fit-for-purpose" through its tiered pricing structure. The company offers three tiers of nonGLP method qualification with increasing accuracy and precision

xyzagen.com

August Bioservices

August Bioservices

August Bioservices is a team of highly experienced life science experts providing rigorous research, pharmaceutical development, and early-phase clinical manufacturing services to clients in the pharmaceutical and biotechnology space. The company's niche offerings in protein-based research ensure that clients devote their hard-won resources to the right molecule. The company delivers meticulous target validation services, sophisticated functional characterization, and advanced assay development. Fragment-based drug discovery with high throughput screening is also one of its specialties

Avid Bioservices

Avid Bioservices

Avid Bioservices is a dedicated contract development and manufacturing organization (CDMO) focused on development and cGMP manufacturing of biopharmaceutical products derived from mammalian cell culture. The company provides a comprehensive range of process development, high quality cGMP clinical and commercial manufacturing services for the biotechnology and biopharmaceutical industries. With 27 years of experience producing monoclonal antibodies and recombinant proteins in batch, fed-batch and perfusion modes, Avid's services include cGMP clinical and commercial product manufacturing, purification, stability testing and regulatory strategy, submission and support. The company also provides a variety of process development activities, including cell line development and optimization, cell culture and feed optimization, analytical methods development and product characterization

BioAgilytix

BioAgilytix

BioAgilytix’s global team of highly experienced scientific and QA professionals deliver world-leading science, proven data integrity, and deep regulatory expertise to support all phases of large molecule global studies. The company provides comprehensive GxP services to innovators all over the world, including many of the top global pharmaceutical and biotech companies. The company is committed as its customers to advancing new biologic products that can change and save lives, and it supports these efforts by helping them navigate the complex scientific and regulatory challenges inherent in the bioanalytical testing of these drugs

Worldwide Clinical Trials

Worldwide Clinical Trials

Worldwide is the first customer-centric CRO founded by physicians dedicated to advancing medical science and built on an unwavering commitment to operational excellence. The company strategically balances science, medicine, operations, and commercial intelligence to achieve successful drug development. Its mission is to bring better products to market and improve patients’ lives through our clinical trial services. Worldwide is a group of clinicians, scientists, researchers, and tech wizards who facilitate the development of life-changing medicines. The company does this with operational acumen, savvy decision-making, deft management, and commercial intelligence—all bolstered by science and medicine